Vitamin B 12 deficiency causes megaloblastic anemia. There are many people around the world who suffer from megaloblastic anemia. Megaloblasts form as a result of delayed maturation of the nuclear maturation of the erythroblasts. The proper maturation of nuclear materials needs Vitamin B 12 as well as folic acid.
When a person is diagnosed to have megaloblastic anemia due to vitamin B 12 deficiency,, they are treated with vitamin B 12. People with vitamin B 12 deficiency develop many symptoms such as polyneuropathy, loss of vibration sense, etc.Once the diagnosis is made as vitamin B 12 deficiency, the patient is supplemented with the deprived agent.
The most important question is 'how long will it take for these symptoms to dissappear?'. After 2 days of therapy, the patient may start to feel better. The investigations will show reticulocytosis 2-3 days after starting therapy. Some people with vitamin B12 deficienccy, has lower limb numbness indicating polyneuropathy, which might take 6-12 months to resolve.
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